The first episode of Laverne & Shirley hit the small screen 40 years ago today — and the cast has changed a lot since the show's premiere in 1976!

RELATED: Laverne & Shirley Stars Cindy Williams and Penny Marshall Share Memories From the Set for the Show's 40th Anniversary!

To celebrate the show's anniversary, click through the gallery below to see what the cast — including Penny Marshall, Cindy Williams and more! — is up to today!

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Penny Marshall (Laverne DeFazio)

Since her lead role on Laverne & Shirley, Penny, 73, has had an extremely successful directing and producing career. Over the years she has directed Big, Awakenings and A League of Their Own and produced Cinderella Man, _ Bewitched_ and a few episodes of According to Jim.

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Cindy Williams (Shirley Feeney)

After starring as Laverne's best friend, the 69-year-old actress appeared on TV series' Getting By and Normal Life. She also had minor roles on shows 8 Simple Rules and The Magic School Bus and appeared in TV movies Earth Angel and Steel Magnolias.

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David L. Lander (Andrew "Squiggy" Squiggman)

The 68-year-old actor and comedian — who was diagnosed with multiple sclerosis in 1984 — continued his long and successful showbiz career by appearing on shows Midnight Patrol: Adventures in the Dream Zone, Tattooed Teenage Alien Fighters from Beverly Hills, Pacific Blue and 101 Dalmatians: The Series. He also had roles in movies A Bug's Life and Scary Movie.

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Michael McKean (Leonard "Lenny" Kosniwski)

After starring on Laverne & Shirley, the 68-year-old actor landed roles on shows including 101 Dalmatians: The Series, Jungle Cubs and Saturday Night Live. He also appeared in movies Planes, Trains & Automobiles and Whatever Works.

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Eddie Mekka (Carmine "The Big Ragoo" Ragusa)

After Laverne & Shirley, the 63-year-old actor appeared on shows Family Matters, The Bold and the Beautiful and The Young and Restless.

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Phil Foster (Frank DeFazio)

Shortly after playing Frank on Laverne & Shirley, Phil sadly died of heart failure in 1985. He was 72-years-old.

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Betty Garrett (Edna Babish)

After Laverne & Shirley, the actress appeared in TV series' Murder, She Wrote, The Golden Girls and Grey's Anatomy. She sadly died after suffering an aortic aneurysm in 2011. She was 91-years-old.

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